PESA (Percutaneous Epididymal Sperm Aspiration)

PESA (Percutaneous Epididymal Sperm Aspiration)

Percutaneous Epididymal Sperm Aspiration (PESA) is a revolutionary procedure designed to aid men facing infertility due to various sperm-related issues. This technique involves the extraction of sperm directly from the testicles using a fine needle, offering new hope to couples striving to become parents.


Compared to traditional In Vitro Fertilization (IVF), PESA provides a more targeted and successful approach to help men with male infertility achieve their dreams of parenthood. Some fertility clinics offer PESA for all infertility patients, regardless of their diagnosis. In this method, a single sperm is directly injected into a single egg, increasing the likelihood of fertilization.


PESA is typically recommended for men experiencing the following conditions of male infertility:


PESA is a laboratory-based procedure, meticulously executed to optimize fertilization. The process involves selecting a single sperm with the aid of a fine glass needle and directly injecting it into the egg’s cytoplasm. This method offers a higher chance of fertilization compared to traditional IVF, where multiple sperm are required to achieve fertilization. Stimulation of the ovaries is essential to ensure egg maturation, and this is achieved by using medications, similar to the IVF process.

Once the eggs have matured, they are retrieved through a procedure known as Follicular Puncture, conducted in the laboratory where matured follicles are collected. The best quality sperm is carefully selected, and the ICSI procedure is performed. Following fertilization, the embryos are cultured in the laboratory for 3 to 5 days. Subsequently, the fertilized eggs are transferred back into the uterus with a cannula, allowing the embryo to implant against the uterine lining for further development. Any remaining embryos can be vitrified for use in later cycles, eliminating the need for ovarian stimulation.


After PESA, your healthcare provider closely monitors the fertilized egg in the laboratory for signs of successful fertilization. Typically, a healthy fertilized egg should divide into cells and form a blastocyst within five to six days. The success rate of PESA is approximately around 60-65%, providing renewed hope for couples aspiring to become parents.